Disease: Diabetic Neuropathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDKRB1 P46663 bradykinin receptor B1 G-protein coupled receptor 4.7E-03 0.619 0.731
ACSL1 P33121 acyl-CoA synthetase long chain family member 1 Enzyme 1.5E-03 0.617 0.577
CHRM2 P08172 cholinergic receptor muscarinic 2 G-protein coupled receptor 0.18 0.585 0.615
IRS2 Q9Y4H2 insulin receptor substrate 2 0.99 0.535 0.654
SREBF1 P36956 sterol regulatory element binding transcription factor 1 1.5E-02 0.518 0.808
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808
PRKCD Q05655 protein kinase C delta Kinase 1.00 0.480 0.846
GPX1 P07203 glutathione peroxidase 1 Enzyme 3.9E-05 0.458 0.923
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
FOXO3 O43524 forkhead box O3 0.99 0.431 0.808
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923