Disease: Diabetic Neuropathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
FOXO3 O43524 forkhead box O3 0.99 0.431 0.808
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
GPX1 P07203 glutathione peroxidase 1 Enzyme 3.9E-05 0.458 0.923
PRKCD Q05655 protein kinase C delta Kinase 1.00 0.480 0.846
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808