Disease: Depressive disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
RORA P35398 RAR related orphan receptor A Nuclear receptor 0.40 0.533 0.808
LEP P41159 leptin 0.46 0.349 0.846
PDE4B Q07343 phosphodiesterase 4B 0.47 0.566 0.731
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CADM1 Q9BY67 cell adhesion molecule 1 0.66 0.491 0.769
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
PDE4A P27815 phosphodiesterase 4A 0.98 0.523 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
NPAS2 Q99743 neuronal PAS domain protein 2 1.00 0.595 0.654
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808