Disease: bone destruction
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
GFI1 Q99684 growth factor independent 1 transcriptional repressor Transcription factor 0.25 0.546 0.769
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
NFKB2 Q00653 nuclear factor kappa B subunit 2 Transcription factor 1.00 0.509 0.808
SND1 Q7KZF4 staphylococcal nuclease and tudor domain containing 1 Transcription factor 0.98 0.576 0.769
ZBTB7A O95365 zinc finger and BTB domain containing 7A Transcription factor 0.96 0.564 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BMP6 P22004 bone morphogenetic protein 6 Signaling 0.76 0.531 0.808
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
CCN1 O00622 cellular communication network factor 1 Signaling 0.71 0.473 0.731
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCL3 P10147 C-C motif chemokine ligand 3 Signaling 0.35 0.460 0.885
PMEL P40967 premelanosome protein Signaling 3.1E-18 0.531 0.769
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TRAF3 Q13114 TNF receptor associated factor 3 Signaling 1.00 0.541 0.769
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846
TNFSF14 O43557 TNF superfamily member 14 Signaling 5.2E-02 0.529 0.769
SEMA3A Q14563 semaphorin 3A Signaling 0.98 0.500 0.808
SEMA4D Q92854 semaphorin 4D Signaling 0.97 0.564 0.769
NCOA5 Q9HCD5 nuclear receptor coactivator 5 Receptor 1.00 0.631 0.692
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923