Disease: Hypertrophic obstructive cardiomyopathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
RYR2 Q92736 ryanodine receptor 2 Ion channel 1.00 0.539 0.615
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
FLNC Q14315 filamin C 1.00 0.568 0.615
ACTN2 P35609 actinin alpha 2 1.00 0.686 0.462
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
LMNA P02545 lamin A/C 1.00 0.384 0.885
PRMT1 Q99873 protein arginine methyltransferase 1 Epigenetic regulator 1.00 0.552 0.808
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
ACTC1 P68032 actin alpha cardiac muscle 1 Cellular structure 0.74 0.610 0.538
TNNC1 P63316 troponin C1, slow skeletal and cardiac type Calcium-binding protein 0.68 0.647 0.462
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
PLN P26678 phospholamban 0.45 0.595 0.577
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
LAMP2 P13473 lysosomal associated membrane protein 2 Transporter 0.27 0.552 0.731