Disease: Hypertrophic obstructive cardiomyopathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
TRNI tRNA 0.743 0.385
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
OBSCN Q5VST9 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF Kinase 1.9E-164 0.736 0.538
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
NRAP Q86VF7 nebulin related anchoring protein 3.3E-50 0.861 0.115
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
MYH6 P13533 myosin heavy chain 6 1.6E-32 0.581 0.615
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
PLA2G7 Q13093 phospholipase A2 group VII Enzyme 5.3E-22 0.537 0.769
ELAC2 Q9BQ52 elaC ribonuclease Z 2 1.7E-20 0.670 0.346
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692
ACADVL P49748 acyl-CoA dehydrogenase very long chain Enzyme 4.2E-15 0.653 0.654
SURF1 Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 1.6E-13 0.578 0.654
NEXN Q0ZGT2 nexilin F-actin binding protein 3.9E-11 0.695 0.269
MYBPC3 Q14896 myosin binding protein C3 8.0E-11 0.593 0.385
ANKRD1 Q15327 ankyrin repeat domain 1 2.6E-10 0.628 0.692
DSG2 Q14126 desmoglein 2 Cell adhesion 2.8E-10 0.601 0.692
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
ITGB1BP2 Q9UKP3 integrin subunit beta 1 binding protein 2 Signaling 2.6E-08 0.821 0.038
MYL2 P10916 myosin light chain 2 Calcium-binding protein 2.7E-08 0.601 0.615
ACAD9 Q9H845 acyl-CoA dehydrogenase family member 9 Enzyme 4.5E-08 0.722 0.269
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923