Disease: precancerous lesions
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
SLC12A9 Q9BXP2 solute carrier family 12 member 9 Transporter 1.2E-15 0.454 0.769
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
CDH1 P12830 cadherin 1 0.15 0.401 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
PCDH10 Q9P2E7 protocadherin 10 0.89 0.582 0.769
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962