Disease: precancerous lesions
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CSF1 P09603 colony stimulating factor 1 1.00 0.473 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
PCDH10 Q9P2E7 protocadherin 10 0.89 0.582 0.769
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885