Disease: HER2 gene amplification
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
UVRAG Q9P2Y5 UV radiation resistance associated 0.99 0.436 0.769
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
TMED7 Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 0.48 0.436 0.808
TICAM2 Q86XR7 Q9Y3B3 toll like receptor adaptor molecule 2 2.6E-03 0.438 0.769
TMED7-TICAM2 Q86XR7 Q9Y3B3 TMED7-TICAM2 readthrough 2.6E-03 0.438 0.769
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
IFI27 P40305 interferon alpha inducible protein 27 1.1E-02 0.437 0.769
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
YY1 P25490 YY1 transcription factor Transcription factor 0.99 0.481 0.808
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
RARB P10826 retinoic acid receptor beta Nuclear receptor 1.00 0.478 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885