Disease: Charcot-Marie-Tooth Disease, Type Ia (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
CANX P27824 calnexin Chaperone 0.87 0.582 0.769
CNTF P26441 ciliary neurotrophic factor 2.3E-05 0.561 0.615
COX10 Q12887 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 Enzyme 8.4E-02 0.623 0.654
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
HOXD10 P28358 homeobox D10 6.3E-02 0.590 0.538
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
LITAF Q99732 lipopolysaccharide induced TNF factor Transcription factor 3.1E-02 0.650 0.462
LRSAM1 Q6UWE0 leucine rich repeat and sterile alpha motif containing 1 3.1E-13 0.638 0.500
MAG P20916 myelin associated glycoprotein Receptor 0.49 0.579 0.692
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
MORC2 Q9Y6X9 MORC family CW-type zinc finger 2 1.00 0.626 0.462
MPZ P25189 myelin protein zero 0.27 0.503 0.846
NDRG1 Q92597 N-myc downstream regulated 1 Enzyme 1.1E-02 0.488 0.731
NEFL P07196 neurofilament light 0.488 0.769
NTF3 P20783 neurotrophin 3 Signaling 0.93 0.519 0.808
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
PXMP2 Q9NR77 peroxisomal membrane protein 2 Receptor 9.2E-03 0.743 0.192
RER1 O15258 retention in endoplasmic reticulum sorting receptor 1 0.38 0.821 0.231
RNMT O43148 RNA guanine-7 methyltransferase 5.7E-05 0.647 0.500
SLC25A46 Q96AG3 solute carrier family 25 member 46 Transporter 1.3E-05 0.695 0.308
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808