Disease: Cholestasis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
CTHRC1 Q96CG8 collagen triple helix repeat containing 1 Enzyme 2.7E-05 0.556 0.692
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CXCR3 P49682 C-X-C motif chemokine receptor 3 G-protein coupled receptor 0.18 0.436 0.808
CYGB Q8WWM9 cytoglobin 0.10 0.579 0.577
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
CYP7A1 P22680 cytochrome P450 family 7 subfamily A member 1 Enzyme 2.5E-04 0.576 0.615
DEFB1 P60022 defensin beta 1 0.41 0.509 0.808
DLAT P10515 dihydrolipoamide S-acetyltransferase 2.3E-08 0.576 0.731
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FBL P22087 fibrillarin Enzyme 0.99 0.572 0.654
FGF19 O95750 fibroblast growth factor 19 Signaling 0.57 0.548 0.615
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
GGT1 P19440 gamma-glutamyltransferase 1 Enzyme 7.5E-05 0.496 0.885
GGT2 P36268 gamma-glutamyltransferase 2 1.3E-04 0.513 0.846
GGTLC1 Q9BX51 gamma-glutamyltransferase light chain 1 Enzyme 3.3E-05 0.559 0.731
GGTLC3 B5MD39 gamma-glutamyltransferase light chain family member 3 0.513 0.846
GGTLC4P gamma-glutamyltransferase light chain 4 pseudogene 0.513 0.846
GGTLC5P gamma-glutamyltransferase light chain 5 pseudogene 0.513 0.846
GPBAR1 Q8TDU6 G protein-coupled bile acid receptor 1 G-protein coupled receptor 1.4E-09 0.548 0.731
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923