Disease: Anemia, Sickle Cell
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ARG1 P05089 arginase 1 Enzyme 3.6E-04 0.476 0.846
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885
CHIT1 Q13231 chitinase 1 7.2E-16 0.525 0.692
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
FCGR2A P12318 Fc fragment of IgG receptor IIa Cell adhesion 2.0E-06 0.480 0.769
FCGR3A P08637 Fc fragment of IgG receptor IIIa Cell adhesion 3.7E-06 0.432 0.962
FCGR3B O75015 Fc fragment of IgG receptor IIIb Cell adhesion 3.0E-07 0.452 0.962
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL5 P05113 interleukin 5 5.7E-03 0.437 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
ITGAL P20701 integrin subunit alpha L 4.3E-03 0.511 0.885
ITGB2 P05107 integrin subunit beta 2 Receptor 5.1E-15 0.444 0.923
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MBL2 P11226 mannose binding lectin 2 Receptor 2.7E-03 0.390 0.846
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962