Disease: Aortic Valve Insufficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TMED10P1 transmembrane p24 trafficking protein 10 pseudogene 1 0.663 0.615
MIR155 microRNA 155 0.384 0.885
H3P17 H3 histone pseudogene 17 0.674 0.615
H3P40 H3 histone pseudogene 40 0.506 0.846
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
ASCC1 Q8N9N2 activating signal cointegrator 1 complex subunit 1 2.6E-14 0.495 0.846
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
SLCO6A1 Q86UG4 solute carrier organic anion transporter family member 6A1 Transporter 2.9E-11 0.412 0.885
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
GSTK1 Q9Y2Q3 glutathione S-transferase kappa 1 1.9E-06 0.412 0.885
EPHA3 P29320 EPH receptor A3 Kinase 1.2E-05 0.497 0.692
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769
CLU P10909 clusterin 7.8E-05 0.426 0.885
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
TFPI2 P48307 tissue factor pathway inhibitor 2 Enzyme modulator 8.4E-04 0.521 0.769
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962