Disease: Aortic Valve Insufficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TMED10P1 transmembrane p24 trafficking protein 10 pseudogene 1 0.663 0.615
MIR155 microRNA 155 0.384 0.885
H3P17 H3 histone pseudogene 17 0.674 0.615
H3P40 H3 histone pseudogene 40 0.506 0.846
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885