Disease: Rett Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ADARB1 P78563 adenosine deaminase RNA specific B1 Enzyme 0.80 0.588 0.654
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ARSD P51689 arylsulfatase D Enzyme 1.6E-03 0.535 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CTCF P49711 CCCTC-binding factor Transcription factor 1.00 0.504 0.769
EIF4E P06730 eukaryotic translation initiation factor 4E Nucleic acid binding 0.94 0.448 0.846
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
GABRD O14764 gamma-aminobutyric acid type A receptor subunit delta Ion channel 0.99 0.558 0.692
GRIA2 P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 1.00 0.573 0.692
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
MBD5 Q9P267 methyl-CpG binding domain protein 5 1.00 0.581 0.808
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MED18 Q9BUE0 mediator complex subunit 18 1.6E-04 0.736 0.423
NUP98 P52948 nucleoporin 98 and 96 precursor Enzyme 1.00 0.532 0.577
SLC12A2 P55011 solute carrier family 12 member 2 Transporter 0.96 0.552 0.808
SLC6A8 P48029 solute carrier family 6 member 8 Transporter 1.00 0.476 0.846
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SRY Q05066 sex determining region Y Transcription factor 0.456 0.808