Disease: Hypercholesterolemia, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CYP7A1 P22680 cytochrome P450 family 7 subfamily A member 1 Enzyme 2.5E-04 0.576 0.615
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHX2 P34913 epoxide hydrolase 2 Enzyme 1.8E-21 0.568 0.654
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
GHR P10912 growth hormone receptor Signaling 8.4E-05 0.490 0.846
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
HDL3 Huntington-like neurodegenerative disorder 2 0.663 0.423
HMGA2 P52926 high mobility group AT-hook 2 Nucleic acid binding 0.87 0.429 0.808
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
INSIG2 Q9Y5U4 insulin induced gene 2 6.0E-02 0.653 0.500
ITGB2 P05107 integrin subunit beta 2 Receptor 5.1E-15 0.444 0.923
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LDLRAP1 Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 6.5E-06 0.641 0.538
LINC01194 long intergenic non-protein coding RNA 1194 0.470 0.769
LINC01672 long intergenic non-protein coding RNA 1672 0.462 0.846