Disease: Pregnancy associated hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
VCAM1 P19320 vascular cell adhesion molecule 1 0.80 0.422 0.808
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808