Disease: Pregnancy associated hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808
VCAM1 P19320 vascular cell adhesion molecule 1 0.80 0.422 0.808
MIR204 microRNA 204 0.487 0.808
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
GPR182 O15218 G protein-coupled receptor 182 G-protein coupled receptor 1.4E-04 0.691 0.462
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
RAMP2 O60895 receptor activity modifying protein 2 Receptor 5.1E-02 0.626 0.654
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846