Disease: Hypogonadotropic hypogonadism
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
LEP P41159 leptin 0.46 0.349 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
LMNA P02545 lamin A/C 1.00 0.384 0.885
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
SHBG P04278 sex hormone binding globulin 1.3E-06 0.438 0.808
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
S100A4 P26447 S100 calcium binding protein A4 Calcium-binding protein 6.2E-03 0.448 0.769
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
AMH P03971 anti-Mullerian hormone 3.4E-12 0.476 0.846
NR0B1 P51843 nuclear receptor subfamily 0 group B member 1 Nuclear receptor 0.97 0.494 0.808
FGF8 P55075 fibroblast growth factor 8 Signaling 0.68 0.507 0.769
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769