Disease: Hypogonadotropic hypogonadism
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TACR3 P29371 tachykinin receptor 3 G-protein coupled receptor 1.8E-17 0.553 0.769
PNPLA6 Q8IY17 patatin like phospholipase domain containing 6 Enzyme 1.9E-13 0.533 0.769
AMH P03971 anti-Mullerian hormone 3.4E-12 0.476 0.846
RBM28 Q9NW13 RNA binding motif protein 28 6.2E-12 0.682 0.423
STAR P49675 steroidogenic acute regulatory protein 8.8E-11 0.513 0.808
PCSK1 P29120 proprotein convertase subtilisin/kexin type 1 Enzyme 2.7E-09 0.548 0.615
SEMA3E O15041 semaphorin 3E Signaling 8.7E-09 0.515 0.769
SERPINA4 P29622 serpin family A member 4 Enzyme modulator 9.7E-09 0.641 0.654
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
SLC29A3 Q9BZD2 solute carrier family 29 member 3 Transporter 1.3E-07 0.578 0.769
RAB3GAP1 Q15042 RAB3 GTPase activating protein catalytic subunit 1 1.5E-07 0.566 0.692
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
DCAF17 Q5H9S7 DDB1 and CUL4 associated factor 17 3.7E-07 0.653 0.577
IL17RD Q8NFM7 interleukin 17 receptor D 1.1E-06 0.617 0.654
SHBG P04278 sex hormone binding globulin 1.3E-06 0.438 0.808
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769
PROKR2 Q8NFJ6 prokineticin receptor 2 G-protein coupled receptor 2.4E-06 0.538 0.731
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
PDE5A O76074 phosphodiesterase 5A 1.1E-04 0.513 0.731
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
MC4R P32245 melanocortin 4 receptor G-protein coupled receptor 9.2E-04 0.535 0.692
LHB P01229 luteinizing hormone subunit beta Signaling 2.2E-03 0.638 0.462
HJV Q6ZVN8 hemojuvelin BMP co-receptor 4.2E-03 0.621 0.654
S100A4 P26447 S100 calcium binding protein A4 Calcium-binding protein 6.2E-03 0.448 0.769