Disease: Obesity, Morbid
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
LEP P41159 leptin 0.46 0.349 0.846
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
CD68 P34810 CD68 molecule Transporter 1.4E-06 0.408 0.808
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
RETN Q9HD89 resistin 3.7E-02 0.454 0.808
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
SCD O00767 stearoyl-CoA desaturase 0.97 0.490 0.808