Disease: Obesity, Morbid
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACACB O00763 acetyl-CoA carboxylase beta 7.6E-47 0.644 0.654
ADCY3 O60266 adenylate cyclase 3 2.0E-11 0.678 0.615
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
LEP P41159 leptin 0.46 0.349 0.846
LIPE Q05469 lipase E, hormone sensitive type 9.7E-12 0.599 0.500
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
SCD O00767 stearoyl-CoA desaturase 0.97 0.490 0.808
IRS2 Q9Y4H2 insulin receptor substrate 2 0.99 0.535 0.654
APLN Q9ULZ1 apelin 0.46 0.497 0.769
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
RETN Q9HD89 resistin 3.7E-02 0.454 0.808
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846
CEP19 Q96LK0 centrosomal protein 19 1.6E-02 0.729 0.346
NEUROD1 Q13562 neuronal differentiation 1 Enzyme 0.77 0.543 0.808
ENPP1 P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 5.0E-08 0.498 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
MC4R P32245 melanocortin 4 receptor G-protein coupled receptor 9.2E-04 0.535 0.692