Disease: Tumor Initiation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
FZD4 Q9ULV1 frizzled class receptor 4 G-protein coupled receptor 0.97 0.490 0.923
LPAR3 Q9UBY5 lysophosphatidic acid receptor 3 G-protein coupled receptor 0.68 0.509 0.923
LGR6 Q9HBX8 leucine rich repeat containing G protein-coupled receptor 6 G-protein coupled receptor 2.9E-06 0.502 0.923
MRGPRX3 Q96LB0 MAS related GPR family member X3 G-protein coupled receptor 0.529 0.923
MRGPRX4 Q96LA9 MAS related GPR family member X4 G-protein coupled receptor 0.531 0.923
GPR151 Q8TDV0 G protein-coupled receptor 151 G-protein coupled receptor 3.2E-08 0.530 0.923
OXER1 Q8TDS5 oxoeicosanoid receptor 1 G-protein coupled receptor 7.3E-08 0.529 0.923
GPRC6A Q5T6X5 G protein-coupled receptor class C group 6 member A G-protein coupled receptor 5.6E-17 0.526 0.923
MRGPRX1 Q96LB2 MAS related GPR family member X1 G-protein coupled receptor 0.531 0.923
VN1R17P Q8TDU5 vomeronasal 1 receptor 17 pseudogene 0.529 0.923
GPR166P G protein-coupled receptor 166 pseudogene 0.531 0.923