Disease: Tumor Initiation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WWTR1 Q9GZV5 WW domain containing transcription regulator 1 Enzyme modulator 0.94 0.529 0.615
EPHA3 P29320 EPH receptor A3 Kinase 1.2E-05 0.497 0.692
SIX1 Q15475 SIX homeobox 1 Transcription factor 0.65 0.496 0.692
MIR20A microRNA 20a 0.498 0.769
DDR1 Q08345 discoidin domain receptor tyrosine kinase 1 Kinase 4.6E-06 0.497 0.808
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
TAZ Q16635 tafazzin Enzyme 0.73 0.477 0.808
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
ADRA1A P35348 adrenoceptor alpha 1A G-protein coupled receptor 3.4E-07 0.462 0.846
ADRA2B P18089 adrenoceptor alpha 2B G-protein coupled receptor 4.5E-06 0.465 0.846
B2M P61769 beta-2-microglobulin Immune response 0.56 0.447 0.846
BRS3 P32247 bombesin receptor subtype 3 G-protein coupled receptor 0.95 0.474 0.846
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
GPR42 O15529 G protein-coupled receptor 42 (gene/pseudogene) G-protein coupled receptor 5.1E-02 0.475 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
SSTR4 P31391 somatostatin receptor 4 G-protein coupled receptor 3.7E-13 0.469 0.846
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846