Disease: Memory Impairment, CTCAE 3.0
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
KCNQ2 O43526 potassium voltage-gated channel subfamily Q member 2 Ion channel 1.00 0.537 0.654
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
PSAP P07602 prosaposin 0.99 0.532 0.846
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
KCNQ3 O43525 potassium voltage-gated channel subfamily Q member 3 Ion channel 0.80 0.604 0.462
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
RPS20 P60866 ribosomal protein S20 Nucleic acid binding 2.1E-02 0.610 0.692
TWNK Q96RR1 twinkle mtDNA helicase Enzyme 3.2E-03 0.516 0.692
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
SEMA4A Q9H3S1 semaphorin 4A Signaling 1.8E-05 0.569 0.692
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
MLH3 Q9UHC1 mutL homolog 3 Nucleic acid binding 4.9E-08 0.582 0.538
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769