Disease: Memory Impairment, CTCAE 3.0
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
FAN1 Q9Y2M0 FANCD2 and FANCI associated nuclease 1 1.7E-25 0.610 0.577
PAH P00439 phenylalanine hydroxylase 6.4E-23 0.516 0.769
PMS1 P54277 PMS1 homolog 1, mismatch repair system component Nucleic acid binding 1.3E-17 0.569 0.654
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462
MLH3 Q9UHC1 mutL homolog 3 Nucleic acid binding 4.9E-08 0.582 0.538
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
SEMA4A Q9H3S1 semaphorin 4A Signaling 1.8E-05 0.569 0.692
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
TWNK Q96RR1 twinkle mtDNA helicase Enzyme 3.2E-03 0.516 0.692
RPS20 P60866 ribosomal protein S20 Nucleic acid binding 2.1E-02 0.610 0.692
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
KCNQ3 O43525 potassium voltage-gated channel subfamily Q member 3 Ion channel 0.80 0.604 0.462
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808