Disease: Congenital defects
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTCH1 Q13635 patched 1 1.00 0.398 0.885
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PTK7 Q13308 protein tyrosine kinase 7 (inactive) Kinase 1.00 0.568 0.615
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ZIC2 O95409 Zic family member 2 Transcription factor 0.97 0.556 0.769
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
ZIC3 O60481 Zic family member 3 Transcription factor 0.92 0.587 0.423
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
MSX2 P35548 msh homeobox 2 Transcription factor 0.26 0.539 0.769
PAX3 P23760 paired box 3 0.24 0.481 0.769
FOLR1 P15328 folate receptor alpha 0.13 0.522 0.885
SLC46A1 Q96NT5 solute carrier family 46 member 1 Transporter 2.2E-02 0.606 0.731
MTHFD1 P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 4.5E-03 0.554 0.769
TCN2 P20062 transcobalamin 2 1.0E-06 0.578 0.615
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923
MTHFD1L Q6UB35 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Enzyme 1.9E-12 0.674 0.538
FUT2 Q10981 fucosyltransferase 2 Enzyme 5.3E-14 0.552 0.731