Disease: Congenital defects
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 0.534 0.731
CUBN O60494 cubilin 4.6E-42 0.587 0.769
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
SHMT1 P34896 serine hydroxymethyltransferase 1 Enzyme 1.3E-14 0.566 0.654
NAT1 P18440 N-acetyltransferase 1 Enzyme 1.9E-14 0.536 0.846
FUT2 Q10981 fucosyltransferase 2 Enzyme 5.3E-14 0.552 0.731
MTHFD1L Q6UB35 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Enzyme 1.9E-12 0.674 0.538
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
TCN2 P20062 transcobalamin 2 1.0E-06 0.578 0.615
MTHFD1 P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 4.5E-03 0.554 0.769
SLC46A1 Q96NT5 solute carrier family 46 member 1 Transporter 2.2E-02 0.606 0.731
FOLR1 P15328 folate receptor alpha 0.13 0.522 0.885
PAX3 P23760 paired box 3 0.24 0.481 0.769
MSX2 P35548 msh homeobox 2 Transcription factor 0.26 0.539 0.769
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IFNG P01579 interferon gamma 0.47 0.288 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
ZIC3 O60481 Zic family member 3 Transcription factor 0.92 0.587 0.423
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
ZIC2 O95409 Zic family member 2 Transcription factor 0.97 0.556 0.769