Disease: Aplasia Cutis Congenita
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EN1 Q05925 engrailed homeobox 1 Transcription factor 0.93 0.821 0.269
KRT15 P19012 keratin 15 2.4E-16 0.659 0.538
SPEN Q96T58 spen family transcriptional repressor 1.00 0.644 0.654
MYB P10242 MYB proto-oncogene, transcription factor 0.82 0.490 0.692
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
ITGB4 P16144 integrin subunit beta 4 Receptor 9.5E-19 0.525 0.731
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
MARCKS P29966 myristoylated alanine rich protein kinase C substrate 0.33 0.559 0.769
LEF1 Q9UJU2 lymphoid enhancer binding factor 1 1.00 0.486 0.769
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
ALCAM Q13740 activated leukocyte cell adhesion molecule Cell adhesion 0.73 0.502 0.808
CDH1 P12830 cadherin 1 0.15 0.401 0.808
VCAN P13611 versican Extracellular structure 1.00 0.497 0.808
DAPK1 P53355 death associated protein kinase 1 Kinase 1.00 0.472 0.808
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
PLAG1 Q6DJT9 PLAG1 zinc finger Transcription factor 1.00 0.493 0.808
SOX4 Q06945 SRY-box transcription factor 4 Transcription factor 0.93 0.489 0.808
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
PRKD1 Q15139 protein kinase D1 Kinase 6.6E-07 0.531 0.846
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885