Disease: Aplasia Cutis Congenita
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ITGB4 P16144 integrin subunit beta 4 Receptor 9.5E-19 0.525 0.731
KRT15 P19012 keratin 15 2.4E-16 0.659 0.538
FOLH1 Q04609 folate hydrolase 1 Enzyme 6.2E-09 0.453 0.885
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885
PRKD1 Q15139 protein kinase D1 Kinase 6.6E-07 0.531 0.846
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
CDH1 P12830 cadherin 1 0.15 0.401 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
MARCKS P29966 myristoylated alanine rich protein kinase C substrate 0.33 0.559 0.769
ACKR3 P25106 atypical chemokine receptor 3 G-protein coupled receptor 0.39 0.428 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
ALCAM Q13740 activated leukocyte cell adhesion molecule Cell adhesion 0.73 0.502 0.808
MYB P10242 MYB proto-oncogene, transcription factor 0.82 0.490 0.692
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
SOX4 Q06945 SRY-box transcription factor 4 Transcription factor 0.93 0.489 0.808
EN1 Q05925 engrailed homeobox 1 Transcription factor 0.93 0.821 0.269
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962