Disease: Spastic Paraplegia, Hereditary
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PDXP Q96GD0 pyridoxal phosphatase Enzyme 0.26 0.533 0.731
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846
NIPA1 Q7RTP0 NIPA magnesium transporter 1 Transporter 5.9E-03 0.682 0.462
MAG P20916 myelin associated glycoprotein Receptor 0.49 0.579 0.692
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
KY Q8NBH2 kyphoscoliosis peptidase 1.5E-10 0.736 0.231
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
KIF1C O43896 kinesin family member 1C Cellular structure 0.72 0.700 0.500
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
IMMT Q16891 inner membrane mitochondrial protein 1.3E-02 0.576 0.846
IFT122 Q9HBG6 intraflagellar transport 122 2.4E-24 0.560 0.846
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
GPT2 Q8TD30 glutamic--pyruvic transaminase 2 Enzyme 3.4E-04 0.650 0.577
GJC2 Q5T442 gap junction protein gamma 2 Cell-cell junction 1.0E-02 0.593 0.692
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
FA2H Q7L5A8 fatty acid 2-hydroxylase Enzyme 0.15 0.573 0.654
ERLIN2 O94905 ER lipid raft associated 2 6.7E-04 0.647 0.500
EPHB1 P54762 EPH receptor B1 Kinase 1.00 0.518 0.846
DYNC1H1 Q14204 dynein cytoplasmic 1 heavy chain 1 Enzyme 1.00 0.547 0.769
DSTYK Q6XUX3 dual serine/threonine and tyrosine protein kinase Kinase 0.51 0.700 0.462
DDHD2 O94830 DDHD domain containing 2 Enzyme 1.4E-10 0.695 0.577
DDHD1 Q8NEL9 DDHD domain containing 1 Enzyme 0.90 0.716 0.423
CYP7B1 O75881 cytochrome P450 family 7 subfamily B member 1 Enzyme 3.3E-06 0.563 0.692