Disease: Hyperreflexia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
KIF1C O43896 kinesin family member 1C Cellular structure 0.72 0.700 0.500
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
KIDINS220 Q9ULH0 kinase D interacting substrate 220 7.4E-02 0.534 0.769
KDM5C P41229 lysine demethylase 5C 1.00 0.581 0.538
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
GPT2 Q8TD30 glutamic--pyruvic transaminase 2 Enzyme 3.4E-04 0.650 0.577
GLRX5 Q86SX6 glutaredoxin 5 Enzyme 0.75 0.659 0.538
GJC2 Q5T442 gap junction protein gamma 2 Cell-cell junction 1.0E-02 0.593 0.692
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
GAN Q9H2C0 gigaxonin 2.5E-02 0.674 0.500
FARS2 O95363 phenylalanyl-tRNA synthetase 2, mitochondrial Enzyme 9.3E-09 0.615 0.731
FAM126A Q9BYI3 family with sequence similarity 126 member A 0.12 0.682 0.423
ERLIN2 O94905 ER lipid raft associated 2 6.7E-04 0.647 0.500
DSTYK Q6XUX3 dual serine/threonine and tyrosine protein kinase Kinase 0.51 0.700 0.462
DDHD2 O94830 DDHD domain containing 2 Enzyme 1.4E-10 0.695 0.577
DDHD1 Q8NEL9 DDHD domain containing 1 Enzyme 0.90 0.716 0.423
CYP7B1 O75881 cytochrome P450 family 7 subfamily B member 1 Enzyme 3.3E-06 0.563 0.692
CPT1C Q8TCG5 carnitine palmitoyltransferase 1C Enzyme 2.2E-09 0.691 0.500
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769