Disease: Alcohol abuse
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
AGRP O00253 agouti related neuropeptide Signaling 7.0E-04 0.488 0.769
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
ARTN Q5T4W7 artemin Signaling 0.36 0.480 0.846
LEP P41159 leptin 0.46 0.349 0.846
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769