Disease: Alcohol abuse
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
AGRP O00253 agouti related neuropeptide Signaling 7.0E-04 0.488 0.769
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
ALDH1A1 P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 0.95 0.460 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808