Disease: Foot dorsiflexor weakness
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LMNA P02545 lamin A/C 1.00 0.384 0.885
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
VCP P55072 valosin containing protein 1.00 0.469 0.923
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
LBR Q14739 lamin B receptor Enzyme 0.18 0.473 0.808
NEFL P07196 neurofilament light 0.488 0.769
MPZ P25189 myelin protein zero 0.27 0.503 0.846
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
AIFM1 O95831 apoptosis inducing factor mitochondria associated 1 Enzyme 1.00 0.527 0.769
TPM2 P07951 tropomyosin 2 Cellular structure 2.4E-04 0.530 0.654
ACTA1 P68133 actin alpha 1, skeletal muscle Cellular structure 1.1E-06 0.540 0.769
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
EGR2 P11161 early growth response 2 Nucleic acid binding 0.50 0.547 0.769
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
DYSF O75923 dysferlin Transporter 3.7E-33 0.582 0.692
MPV17 P39210 mitochondrial inner membrane protein MPV17 Receptor 9.7E-11 0.595 0.577
RAB7A P51149 RAB7A, member RAS oncogene family 0.97 0.597 0.692