Disease: Foot dorsiflexor weakness
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
LMNA P02545 lamin A/C 1.00 0.384 0.885
MPZ P25189 myelin protein zero 0.27 0.503 0.846
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692
NEB P20929 nebulin 4.6E-41 0.608 0.692
NEFL P07196 neurofilament light 0.488 0.769
VCP P55072 valosin containing protein 1.00 0.469 0.923
RAB7A P51149 RAB7A, member RAS oncogene family 0.97 0.597 0.692
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
KLHL41 O60662 kelch like family member 41 1.1E-04 0.682 0.538
MORC2 Q9Y6X9 MORC family CW-type zinc finger 2 1.00 0.626 0.462
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
PRX Q9BXM0 periaxin 2.1E-14 0.650 0.577
INF2 Q27J81 inverted formin, FH2 and WH2 domain containing 0.97 0.644 0.423
COA7 Q96BR5 cytochrome c oxidase assembly factor 7 (putative) 6.0E-02 0.792 0.231
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
LRSAM1 Q6UWE0 leucine rich repeat and sterile alpha motif containing 1 3.1E-13 0.638 0.500
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
ACTA1 P68133 actin alpha 1, skeletal muscle Cellular structure 1.1E-06 0.540 0.769
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
TPM2 P07951 tropomyosin 2 Cellular structure 2.4E-04 0.530 0.654
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
COX6A1 P12074 cytochrome c oxidase subunit 6A1 Enzyme 2.3E-03 0.780 0.154