Disease: Intervertebral Disc Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
CSF1 P09603 colony stimulating factor 1 1.00 0.473 0.808
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
FOSB P53539 FosB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.98 0.463 0.846
SPARC P09486 secreted protein acidic and cysteine rich Signaling 0.89 0.445 0.846
SOST Q9BQB4 sclerostin 0.87 0.474 0.808
JUNB P17275 JunB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.86 0.467 0.769
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
JUND P17535 JunD proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.70 0.475 0.808
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846