Disease: Intervertebral Disc Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
MIR143 microRNA 143 0.462 0.885
MIR15A microRNA 15a 0.482 0.808
MIR182 microRNA 182 0.486 0.846
MIR21 microRNA 21 0.363 0.846
TYRP1 P17643 tyrosinase related protein 1 Enzyme 6.6E-25 0.507 0.846
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885
TRPC6 Q9Y210 transient receptor potential cation channel subfamily C member 6 Ion channel 3.0E-07 0.514 0.692
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
JUN P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 6.0E-02 0.442 0.885