Disease: Intervertebral Disc Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MIR143 microRNA 143 0.462 0.885
MIR15A microRNA 15a 0.482 0.808
MIR182 microRNA 182 0.486 0.846
MIR21 microRNA 21 0.363 0.846
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
PGP A6NDG6 phosphoglycolate phosphatase Enzyme 0.16 0.606 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
SOST Q9BQB4 sclerostin 0.87 0.474 0.808
SPARC P09486 secreted protein acidic and cysteine rich Signaling 0.89 0.445 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TBPL1 P62380 TATA-box binding protein like 1 Transcription factor 0.38 0.506 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962