Disease: Kidney Failure
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SOST Q9BQB4 sclerostin 0.87 0.474 0.808
IGAN1 IgA nephropathy 0.524 0.808
MIR21 microRNA 21 0.363 0.846
CLDN7 O95471 claudin 7 Cell-cell junction 2.9E-03 0.494 0.808
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ADD1 P35611 adducin 1 Cellular structure 0.99 0.612 0.615
KIF3A Q9Y496 kinesin family member 3A Cellular structure 0.90 0.612 0.615
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
LAMA5 O15230 laminin subunit alpha 5 Enzyme modulator 6.5E-03 0.636 0.577
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
NPHS2 Q9NP85 NPHS2 stomatin family member, podocin Enzyme modulator 7.2E-09 0.576 0.538
RAPGEF5 Q92565 Rap guanine nucleotide exchange factor 5 Enzyme modulator 0.98 0.524 0.769
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846