Disease: Sudden Cardiac Death
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ANK2 Q01484 ankyrin 2 1.00 0.626 0.538
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
CASQ2 O14958 calsequestrin 2 1.4E-12 0.691 0.385
CAV3 P56539 caveolin 3 Enzyme modulator 5.5E-03 0.564 0.692
DSC2 Q02487 desmocollin 2 Cell adhesion 5.2E-08 0.610 0.538
DSG2 Q14126 desmoglein 2 Cell adhesion 2.8E-10 0.601 0.692
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
DTNA Q9Y4J8 dystrobrevin alpha 0.63 0.695 0.385
HCN4 Q9Y3Q4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 Ion channel 1.00 0.617 0.269
JUP P14923 junction plakoglobin 8.0E-04 0.628 0.500
KCNE1 P15382 potassium voltage-gated channel subfamily E regulatory subunit 1 Ion channel 3.4E-03 0.588 0.615
KCNE2 Q9Y6J6 potassium voltage-gated channel subfamily E regulatory subunit 2 Ion channel 1.0E-04 0.628 0.423
KCNH2 Q12809 potassium voltage-gated channel subfamily H member 2 Ion channel 1.00 0.522 0.731
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615
KCNJ2 P63252 potassium inwardly rectifying channel subfamily J member 2 Ion channel 0.31 0.572 0.731
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769
LMNA P02545 lamin A/C 1.00 0.384 0.885
MYBPC3 Q14896 myosin binding protein C3 8.0E-11 0.593 0.385
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692
NKX2-5 P52952 NK2 homeobox 5 Transcription factor 0.95 0.533 0.692
NOS1AP O75052 nitric oxide synthase 1 adaptor protein Signaling 0.61 0.608 0.423
PKP2 Q99959 plakophilin 2 Cellular structure 3.1E-18 0.606 0.538
PLN P26678 phospholamban 0.45 0.595 0.577