Disease: Alcohol Use Disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846
ADH1C P00326 alcohol dehydrogenase 1C (class I), gamma polypeptide Enzyme 0.547 0.731
ADH4 P08319 alcohol dehydrogenase 4 (class II), pi polypeptide Enzyme 8.1E-07 0.641 0.462
AKR1A1 P14550 aldo-keto reductase family 1 member A1 Enzyme 6.7E-07 0.510 0.846
ALDH1A1 P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 0.95 0.460 0.846
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
ARNTL2 Q8WYA1 aryl hydrocarbon receptor nuclear translocator like 2 Transcription factor 6.0E-10 0.644 0.654
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CCKAR P32238 cholecystokinin A receptor G-protein coupled receptor 4.0E-03 0.615 0.500
CDK20 Q8IZL9 cyclin dependent kinase 20 Kinase 5.9E-14 0.682 0.462
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885
DDX53 Q86TM3 DEAD-box helicase 53 0.66 0.568 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692