Disease: Neural Tube Defects
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZIC5 Q96T25 Zic family member 5 Transcription factor 0.77 0.711 0.231
ZIC2 O95409 Zic family member 2 Transcription factor 0.97 0.556 0.769
VANGL2 Q9ULK5 VANGL planar cell polarity protein 2 0.84 0.588 0.615
VANGL1 Q8TAA9 VANGL planar cell polarity protein 1 2.0E-02 0.570 0.538
TBXT O15178 T-box transcription factor T Transcription factor 2.4E-02 0.674 0.462
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
PRSS8 Q16651 serine protease 8 Enzyme 0.10 0.641 0.500
SPINT2 O43291 serine peptidase inhibitor, Kunitz type 2 7.5E-04 0.556 0.808
SEC24B O95487 SEC24 homolog B, COPII coat complex component Transporter 1.00 0.890 0.192
SCRIB Q14160 scribble planar cell polarity protein 0.93 0.691 0.423
RRM1 P23921 ribonucleotide reductase catalytic subunit M1 Enzyme 1.00 0.552 0.692
PGPEP1 Q9NXJ5 pyroglutamyl-peptidase I Enzyme 8.5E-03 0.581 0.769
PTK7 Q13308 protein tyrosine kinase 7 (inactive) Kinase 1.00 0.568 0.615
PRCP P42785 prolylcarboxypeptidase Enzyme 8.8E-12 0.633 0.692
PYY P10082 peptide YY Signaling 1.2E-02 0.588 0.615
PAX3 P23760 paired box 3 0.24 0.481 0.769
NPY1R P25929 neuropeptide Y receptor Y1 G-protein coupled receptor 4.3E-02 0.628 0.423
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTHFD1 P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 4.5E-03 0.554 0.769
IFNG P01579 interferon gamma 0.47 0.288 0.962
INS P01308 insulin 0.30 0.445 0.923
GRHL3 Q8TE85 grainyhead like transcription factor 3 Transcription factor 0.99 0.572 0.692
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769