Disease: Neural Tube Defects
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VANGL2 Q9ULK5 VANGL planar cell polarity protein 2 0.84 0.588 0.615
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769
CELSR1 Q9NYQ6 cadherin EGF LAG seven-pass G-type receptor 1 G-protein coupled receptor 1.00 0.700 0.500
DACT1 Q9NYF0 dishevelled binding antagonist of beta catenin 1 0.40 0.547 0.692
PGPEP1 Q9NXJ5 pyroglutamyl-peptidase I Enzyme 8.5E-03 0.581 0.769
CECR2 Q9BXF3 CECR2 histone acetyl-lysine reader Epigenetic regulator 1.00 0.743 0.385
FUZ Q9BT04 fuzzy planar cell polarity protein 1.3E-05 0.597 0.731
ZIC5 Q96T25 Zic family member 5 Transcription factor 0.77 0.711 0.231
BHMT Q93088 betaine--homocysteine S-methyltransferase 3.7E-14 0.595 0.731
GRHL3 Q8TE85 grainyhead like transcription factor 3 Transcription factor 0.99 0.572 0.692
VANGL1 Q8TAA9 VANGL planar cell polarity protein 1 2.0E-02 0.570 0.538
PRSS8 Q16651 serine protease 8 Enzyme 0.10 0.641 0.500
SCRIB Q14160 scribble planar cell polarity protein 0.93 0.691 0.423
PTK7 Q13308 protein tyrosine kinase 7 (inactive) Kinase 1.00 0.568 0.615
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
PRCP P42785 prolylcarboxypeptidase Enzyme 8.8E-12 0.633 0.692
NPY1R P25929 neuropeptide Y receptor Y1 G-protein coupled receptor 4.3E-02 0.628 0.423
RRM1 P23921 ribonucleotide reductase catalytic subunit M1 Enzyme 1.00 0.552 0.692
PAX3 P23760 paired box 3 0.24 0.481 0.769
FOLR1 P15328 folate receptor alpha 0.13 0.522 0.885
FOLR2 P14207 folate receptor beta 5.5E-06 0.559 0.654
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
BMP1 P13497 bone morphogenetic protein 1 8.9E-04 0.554 0.769
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
MTHFD1 P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 4.5E-03 0.554 0.769