Disease: Midface retrusion
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAN2B1 O00754 mannosidase alpha class 2B member 1 4.8E-22 0.674 0.462
SP7 Q8TDD2 Sp7 transcription factor Nucleic acid binding 0.58 0.711 0.462
MEGF8 Q7Z7M0 multiple EGF like domains 8 Enzyme modulator 1.9E-05 0.584 0.538
NXN Q6DKJ4 nucleoredoxin 1.00 0.584 0.577
UPF3B Q9BZI7 UPF3B regulator of nonsense mediated mRNA decay 0.98 0.619 0.615
FZD2 Q14332 frizzled class receptor 2 G-protein coupled receptor 0.65 0.558 0.654
PYCR1 P32322 pyrroline-5-carboxylate reductase 1 2.0E-04 0.570 0.654
B4GALT7 Q9UBV7 beta-1,4-galactosyltransferase 7 1.1E-04 0.628 0.654
SOS2 Q07890 SOS Ras/Rho guanine nucleotide exchange factor 2 Enzyme modulator 1.00 0.608 0.692
A2ML1 A8K2U0 alpha-2-macroglobulin like 1 Enzyme modulator 1.6E-34 0.590 0.692
DVL3 Q92997 dishevelled segment polarity protein 3 Signaling 0.39 0.537 0.731
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731
MRAS O14807 muscle RAS oncogene homolog Enzyme modulator 0.92 0.590 0.731
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
RASA2 Q15283 RAS p21 protein activator 2 Enzyme modulator 7.4E-31 0.579 0.769
RAB3GAP2 Q9H2M9 RAB3 GTPase activating non-catalytic protein subunit 2 Enzyme modulator 0.99 0.584 0.769
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
RRAS P10301 RAS related Enzyme modulator 4.7E-03 0.543 0.808
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
TCOF1 Q13428 treacle ribosome biogenesis factor 1 0.95 0.550 0.808