Disease: Midface retrusion
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
FLNB O75369 filamin B 6.1E-10 0.458 0.923
MAN2B1 O00754 mannosidase alpha class 2B member 1 4.8E-22 0.674 0.462
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
PYCR1 P32322 pyrroline-5-carboxylate reductase 1 2.0E-04 0.570 0.654
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
TCOF1 Q13428 treacle ribosome biogenesis factor 1 0.95 0.550 0.808
LZTR1 Q8N653 leucine zipper like transcription regulator 1 1.0E-92 0.547 0.808
B4GALT7 Q9UBV7 beta-1,4-galactosyltransferase 7 1.1E-04 0.628 0.654
NXN Q6DKJ4 nucleoredoxin 1.00 0.584 0.577
UPF3B Q9BZI7 UPF3B regulator of nonsense mediated mRNA decay 0.98 0.619 0.615
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
MEGF8 Q7Z7M0 multiple EGF like domains 8 Enzyme modulator 1.9E-05 0.584 0.538
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
RASA2 Q15283 RAS p21 protein activator 2 Enzyme modulator 7.4E-31 0.579 0.769
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
RRAS P10301 RAS related Enzyme modulator 4.7E-03 0.543 0.808
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
SOS2 Q07890 SOS Ras/Rho guanine nucleotide exchange factor 2 Enzyme modulator 1.00 0.608 0.692