Disease: secondary acute myeloid leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
CPOX P36551 coproporphyrinogen oxidase Enzyme 0.17 0.488 0.846
THPO P40225 thrombopoietin 0.20 0.513 0.692
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
SEPTIN6 Q14141 septin 6 Enzyme modulator 0.93 0.644 0.385