Disease: secondary acute myeloid leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731
CPOX P36551 coproporphyrinogen oxidase Enzyme 0.17 0.488 0.846
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
THPO P40225 thrombopoietin 0.20 0.513 0.692
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731