Disease: Flexion contracture of proximal interphalangeal joint
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
GPC3 P51654 glypican 3 1.00 0.466 0.808
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
ADAMTS3 O15072 ADAM metallopeptidase with thrombospondin type 1 motif 3 Enzyme 1.0E-10 0.581 0.808
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
FAT4 Q6V0I7 FAT atypical cadherin 4 1.00 0.539 0.808
DHODH Q02127 dihydroorotate dehydrogenase (quinone) Enzyme 3.0E-03 0.576 0.769
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
EFNB1 P98172 ephrin B1 Signaling 0.93 0.561 0.769
GPC4 O75487 glypican 4 0.93 0.547 0.769
IKBKG Q9Y6K9 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Kinase 8.5E-02 0.493 0.769
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 Ion channel 8.1E-07 0.529 0.769
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769
CCBE1 Q6UXH8 collagen and calcium binding EGF domains 1 Calcium-binding protein 1.5E-07 0.585 0.769
DVL3 Q92997 dishevelled segment polarity protein 3 Signaling 0.39 0.537 0.731
FGD1 P98174 FYVE, RhoGEF and PH domain containing 1 Enzyme modulator 1.00 0.573 0.731
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731
NOG Q13253 noggin 0.89 0.518 0.731
CHRNG P07510 cholinergic receptor nicotinic gamma subunit Ion channel 3.3E-19 0.573 0.692