Disease: Spasticity, CTCAE
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
DHDDS Q86SQ9 dehydrodolichyl diphosphate synthase subunit Enzyme 0.25 0.468 0.885
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
SLC1A2 P43004 solute carrier family 1 member 2 Transporter 0.71 0.511 0.731
TPI1 P60174 triosephosphate isomerase 1 Enzyme 3.0E-02 0.517 0.846
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731
STXBP1 P61764 syntaxin binding protein 1 Transporter 1.00 0.532 0.692
KDM5B Q9UGL1 lysine demethylase 5B Epigenetic regulator 7.9E-15 0.532 0.731
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
GABRG2 P18507 gamma-aminobutyric acid type A receptor subunit gamma2 Ion channel 0.74 0.548 0.654
HTT P42858 huntingtin 1.00 0.548 0.654
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
EEF1A2 Q05639 eukaryotic translation elongation factor 1 alpha 2 Enzyme 1.00 0.554 0.808
CLTC Q00610 clathrin heavy chain Transporter 1.00 0.558 0.769
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
HCN1 O60741 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.00 0.564 0.654
PPP3CA Q08209 protein phosphatase 3 catalytic subunit alpha 1.00 0.568 0.769
BCL11B Q9C0K0 BAF chromatin remodeling complex subunit BCL11B Transcription factor 0.99 0.568 0.731